MOLECULES, vol.10, no.3-5, pp.559-571, 2005 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
furan-2,3-dione, pyrazole-3-carboxylic acid, pyrazole-3-carboxylic acid chloride, imidazo [4,5-b]pyridine, IR and NMR spectra, MO calculations, CYCLIC OXALYL COMPOUNDS, HETEROCYCLIC-COMPOUNDS, CYCLIZATION REACTIONS, BIOLOGICAL-ACTIVITY, 4-BENZOYL-2,3-DIOXO-5-PHENYL-2,3-DIHYDROFURAN, 4-BENZOYL-5-PHENYL-2,3-FURANDIONE, 1H-PYRIMIDINES, DERIVATIVES
Kayseri University Affiliated:
The 1H-pyrazole-3-carboxylic acid 2 was converted in good yield (69%) into the corresponding 1H-pyrazole-3-carboxamide 5 via reaction of the acid chloride 3 with 2,3-diaminopyridine (4). A different product, the 3H-imidazo[4,5-b] pyridine derivative 6, was formed from the reaction of 3 with 4 and base in benzene for 5 hours. The structures of the synthesized compounds were determined spectroscopically. The mechanism of the reaction between 3 and 4 was examined theoretically.