Genetically Modified Bacteria: History, Principle and Utility

Azizoğlu U., Thanka P. P., Sudarsanan S. E., Sudheer S., Sharma B. P., Rathoure A.

in: HANDBOOK OF MOLECULAR BIOTECHNOLOGY, Dongyou Liu, Editor, CRC, New York , Florida, pp.1-32, 2024

  • Publication Type: Book Chapter / Chapter Research Book
  • Publication Date: 2024
  • Publisher: CRC, New York 
  • City: Florida
  • Page Numbers: pp.1-32
  • Editors: Dongyou Liu, Editor
  • Kayseri University Affiliated: Yes


Genetically modified bacteria refer to bacteria that have undergone deliberate modification in their genome (DNA/RNA) using recombinant DNA technology and that have acquired distinct genotypic or phenotypic features or properties. GM bacteria containing induced genes of interest can be used to produce a large amount of recombinant proteins. Furthermore, GM bacteria are of great scientific interest as delivery vehicles for biological products and have attracted significant commercial investment. GM bacteria have shown promise for sustainable agricultural development, environmental remediation and therapeutic application, with a slew of new technologies on the horizon.