Investigation of the Relationship between Neutrophil/ Lymphocyte Ratio and Analgesic Consumption in Bimaxillary Orthognathic Surgery Patients# Bimaksiller Ortognatik Cerrahi Hastalarında NLO ve Analjezik Tüketimi Arasındaki İlişki#

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Cumhuriyet Dental Journal, vol.25, pp.34-36, 2022 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 25
  • Publication Date: 2022
  • Doi Number: 10.7126/cumudj.1031144
  • Journal Name: Cumhuriyet Dental Journal
  • Journal Indexes: Scopus, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.34-36
  • Keywords: Neutrophil-Lymphocyte Ratio, Nötrofil-Lenfosit Oranı, Orthognatic Surgery, Ortognatik Cerrahi, Post-Operative Analgesic Drug Consumption, Postoperatif Analjezik İlaç Tüketimi
  • Kayseri University Affiliated: No


© 2022. All Rights Reserved.Objectives: Neutrophil to lymphocyte ratio; as an inexpensive, easily measurable, and repeatable laboratory parameter is an indicator of subclinical inflammation and is also a parameter that gives an idea about the systemic inflammatory response and cellular immune response. In general, lymphopenia reflects the weakness of cellular immunity, while neutrophilia is indicative of the response to systemic inflammation. The ratio of these two values to each other seems to be a marker showing the adequacy of the cellular immune response against this situation, despite the magnitude of systemic inflammation. This study aimed to investigate the relationship between preoperative neutrophil-lymphocyte ratio (NLR) and postoperative analgesic drug consumption. Materials and Methods: Within the scope of the study, the files of 50 patients who underwent bimaxillary orthognathic surgery were retrospectively analysed. The preoperative NLR values of the patients and the need for the analgesic drugs in the first 24 hours and after 24 hours were recorded and correlated. Results: 24% of the patients were girls, and 76% were boys. The average age was 20.54, and the average weight was 65.28 kg. There was a positive, strong, and significant correlation between the preoperative neutrophil count and preoperative NLR value and variables of analgesic drug consumption in the first 24 hours. There was a negative, strong and significant correlation between the preoperative lymphocyte count and the first 24-hour analgesic drug consumption variables. Conclusions: It was concluded that patients with a preoperative NLR value of 2.11 and above might require four or more analgesics in the first 24 hours. Therefore, the NLR value can give preliminary information about the need for postoperative analgesia, and these values could be taken into account when developing a strategy for postoperative analgesia.