Advancements in Entomology, Debasis Mitra,Marika Pellegrini,Beatriz Elena Guerra Sierra, Editör, Springer Singapore, Singapore, ss.269-279, 2026
Pest infestation and exposure to various stressors result in significant losses in agricultural production. Pest management is a critical measure to mitigate these losses. Beyond chemical and biological control methods, genetic control is vital to achieve rapid, sustainable, and enduring pest resistance. Genetic strategies aimed at enhancing plant immunity focus on employing tools, such as CRISPR/Cas9, for gene editing, thereby conferring broad-spectrum resistance to pests in crops. This approach involves direct targeting of viral genomes or insect effectors to minimize yield losses. This chapter provides a summary of genetically modified pest-resistant crop plants, assisting researchers in the selection of crop−/pest-specific genes. Modern techniques, such as CRISPR–Cas, which support the editing of plant genomes to develop pest-resistant crops, are also discussed in this chapter. These methodologies, which include the integration of Bt toxin and precise genome modifications, promote sustainable pest management by reducing reliance on chemical pesticides and mitigating unintended physiological effects in plants. In conclusion, genetic engineering of plant immunity through CRISPR and Bt strategies represents a promising advancement toward a resilient, pesticide-free future, thereby enhancing sustainable crop protection and ensuring global food security.