© 2021 Australian Society of Endodontology Inc.This study investigated the effect of different coronal restorations on the fracture resistance (FR) of immature teeth with simulated regenerative endodontic treatment. A total of 120 lower premolars were divided into eight groups. Except for negative control, the root canals were instrumented with rotary files and Peeso reamers. Fifteen instrumented teeth were acted as positive control (unrestorated). In the remaining 90 teeth, regenerative endodontic treatment procedures were performed. Ninety teeth were randomly divided into 6 groups according to coronal restoration type; Filtek Z550, Filtek Bulk fill Restorative (FBR), SDR+Filtek Z550, EverX+Filtek Z550, Ribbond+FBR and Ribbond+SDR+Filtek Z550. After thermal ageing, the restorated teeth were subjected to vertical loading force. FR values was obtained as follows: Negative control > Ribbond+FBR = Ribbond+SDR+Filtek Z550 > Filtek Z550 = FBR =SDR+Filtek Z550 = EverX+Filtek Z550 > Positive control, (P < 0.05). The use of Ribbond in combination with composite resin enhanced the FR of teeth.