Cyclization Reactions of 1-Pyrimidinyl-3-Arylthiourea Derivatives with Oxalyl Dichloride


Onal Z., Korkusuz E. , İLHAN İ. Ö.

HETEROCYCLIC COMMUNICATIONS, vol.16, pp.79-83, 2010 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 16
  • Publication Date: 2010
  • Title of Journal : HETEROCYCLIC COMMUNICATIONS
  • Page Numbers: pp.79-83

Abstract

N,N-Disubstituted thioureas (1a-g) can be cyclized by use of oxalyl dichloride to the 4,5-dioxo-2-thioxo-perhydro-imidazolyl-pyrimidine-2(H)-thiones (2a-g) in good yields (50-68%). The structures of these compounds were determined by elemental analysis, IR, (1)H NMR and (13)C NMR spectroscopic measurements.