A Simple and Efficient Synthesis of Some Important Pyrazole Derivatives
JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, cilt.37, sa.6, ss.1177-1184, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 6
- Basım Tarihi: 2015
- Dergi Adı: JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1177-1184
- Kayseri Üniversitesi Adresli: Hayır
Özet
The 1H-pyrazole-3-carboxylic acid was converted via reactions of its acid chloride 1a,b with amino acid, thiol and various amine derivatives into the corresponding amino acid ester derivatives 2a-d, 4-aroyl-1,5-diaryl-1H-pyrazol-3-carbotioates 3a-d, and pyrazole-3-carboxamides 6, 7 respectively, in good yields (35-85%). The structures of all new synthesized compounds were established by the 13C NMR, 1H NMR, IR spectroscopic data and elemental analyses.