Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetic acid ethyl ester

Al-Taifi, Elham; Marae, Islam; El-Ossaily, Yasser; Mohamed, Shaaban; Mague, Joel; AKKURT, MEHMET; Bakhite, Etify

doi:10.1107/s2056989022000378

Crystal structure and Hirshfeld surface analysis of 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetic acid ethyl ester

Al-Taifi E. A., Marae I. S., El-Ossaily Y. A., Mohamed S. K., Mague J. T., AKKURT M., ...Daha Fazla

Acta Crystallographica Section E: Crystallographic Communications, cilt.78, ss.220-224, 2022 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 78
Basım Tarihi: 2022
Doi Numarası: 10.1107/s2056989022000378
Dergi Adı: Acta Crystallographica Section E: Crystallographic Communications
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.220-224
Anahtar Kelimeler: crystal structure, tetrahydroisoquinoline, ethyl ester, hydrogen bond, C-H center dot center dot center dot pi(ring), ANALOGS
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Kayseri Üniversitesi Adresli: Hayır

Özet

© 2022.In the title molecule, C25H28N2O5S, (alternative name ethyl 2-{[7-acetyl-4-cyano-6-hydroxy-8-(4-methoxyphenyl)-1,6-dimethyl-5,6,7,8-tetrahydroisoquinolin-3-yl]sulfanyl}acetate) the 4-methoxyphenyl group is disposed on one side of the bicyclic core and the oxygen atoms of the hydroxyl and acetyl groups are disposed on the other side. In the crystal, a layered structure parallel to the ac plane is generated by O - H⋯O and C - H⋯O hydrogen bonds plus C - H⋯π(ring) interactions.