Momordica charantia Seed and Aryl Extracts Potentiate Growth Inhibition and Apoptosis by Dual Blocking of PI3K/AKT and MAPK Pathways as a Downstream Target of EGFR Signaling in Breast Cancer Cells

ŞATIR BAŞARAN, GÜZİDE; Bekci, HATİCE; Baldemir, Ayse; İLGÜN, SELEN; CUMAOĞLU, AHMET

doi:10.2174/1573401315666190712214922

Momordica charantia Seed and Aryl Extracts Potentiate Growth Inhibition and Apoptosis by Dual Blocking of PI3K/AKT and MAPK Pathways as a Downstream Target of EGFR Signaling in Breast Cancer Cells

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ŞATIR BAŞARAN G., Bekci H., Baldemir A., İLGÜN S., CUMAOĞLU A.

CURRENT NUTRITION & FOOD SCIENCE, vol.16, no.5, pp.726-733, 2020 (ESCI)

Publication Type: Article / Article
Volume: 16 Issue: 5
Publication Date: 2020
Doi Number: 10.2174/1573401315666190712214922
Journal Name: CURRENT NUTRITION & FOOD SCIENCE
Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE
Page Numbers: pp.726-733
Kayseri University Affiliated: Yes

Abstract

Background and Objective: Herbal extracts and plant compounds are increasingly becoming of interest for their therapeutic potential in various cancer types. Momordica charantia is well known for its anti-diabetic, anti-inflammatory, and anti-cancer properties.