Pituitary Gland as a Rare Primary Localization of Lymphoma Nadir Bir Primer Lenfoma Lokalizasyonu: Hipofiz Bezi

Özbaş B., CANÖZ Ö., Güven Z., ÖKÇESİZ İ., Dursun H., SELÇUKLU A., ...More

Turkish Journal of Endocrinology and Metabolism, vol.26, no.1, pp.55-60, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.25179/tjem.2021-84943
  • Journal Name: Turkish Journal of Endocrinology and Metabolism
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL, EMBASE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.55-60
  • Keywords: Pituitary tumor, lymphoma, diplopia, headache, visual loss, PRIMARY CNS LYMPHOMA, METHOTREXATE
  • Kayseri University Affiliated: No


© 2022.Lymphomas are the rare causes in the differential diagnosis of pituitary masses. While pituitary infiltration by lymphomas is relatively more frequent, isolated lymphoma associated with the pituitary gland is much rarer. We presented a case of a 64-year-old female patient who was admitted to the hospital due to headache, diplopia and decreased visual acuity. Although the stated preoperative diagnosis was pa-rasellar meningioma, the pathological diagnosis was given as isolated primary pituitary lymphoma after ruling out any other foci. After the definitive diagnosis, the patient under-went chemoradiotherapy. However, despite treatment, the patient died due to pulmonary sepsis. Primary pituitary lymphoma is an extremely rare condition generally seen in elderly and/or immunosuppressive patients. In order to es-tablish an effective therapeutic strategy, it is extremely cru-cial to distinguish between primary and secondary lymphomas. However, the recent evidence for a standardi-zed treatment protocol is still limited due to the small num-ber of cases reported to date.