A NOVEL SYNTHETIC APPROACH TOWARDS 1H-PYRAZOLE-5-CARBOXYLIC ACID DERIVATIVES USING 4-(4-METHYLBENZOYL)-5-(4-METHYLPHENYL)FURAN-2,3-DIONE


Korkusuz E. , YILDIRIM İ., ŞAHİN E.

HETEROCYCLES, vol.87, no.11, pp.2249-2266, 2013 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 87 Issue: 11
  • Publication Date: 2013
  • Doi Number: 10.3987/com-13-12799
  • Title of Journal : HETEROCYCLES
  • Page Numbers: pp.2249-2266

Abstract

The 1H-pyrazole-5-carboxylic acid derivatives were obtained by reactions of 4-(4-methylbenzoyl)-5-(4-methylphenyl)furan-2,3-dione with 2,4-dinitrophenyhydrazine. So, new derivatives of 1H-pyrazole-5-carboxylic acid which are potential biological active compounds, were synthesized for the first time. The structures of all new synthesized products were characterized by JR. H-1-, C-13 NMR, APT, and 2D NMR (HETCOR, COSY) spectroscopic data and elemental