Amino acid-metal phosphate hybrid nanoflowers (AaHNFs): their preparation, characterization and anti-oxidant capacities

ÖZDEMİR N., Altinkaynak C., Türk M., Geçili F., Tavlaşoğlu S.

Polymer Bulletin, vol.79, no.11, pp.9697-9716, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 79 Issue: 11
  • Publication Date: 2022
  • Doi Number: 10.1007/s00289-021-03973-7
  • Journal Name: Polymer Bulletin
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Chemical Abstracts Core, Chimica, Compendex, INSPEC
  • Page Numbers: pp.9697-9716
  • Keywords: Amino acids, Hybrid nanoflowers, Metal ions, Peroxidase-like activity, Anti-oxidant capacity, COMPLEXES, NANOPARTICLES, OXYGEN, DECOLORIZATION, DELIVERY
  • Kayseri University Affiliated: No


© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Reactive oxygen species like hydrogen peroxide have positive roles in vivo systems such as phagocytosis, intercellular signal transfer, regulation of cell growth, and the synthesis of important biological compounds. Nanostructures can exhibit increased redox and radical scavenging activities compared to the free form with peroxidase-like activities. This work presents the synthesis and characterization of amino acid-metal phosphate hybrid nanoflowers (AaHNFs) and their potential as a radical scavenger and anti-oxidant. The AaHNFs were synthesized using some metal ions (Cu2+, Mn2+, Ni2+, Co2+, and Zn2+) and selected amino acids (His, Cys, Asn, and Asp) which contain an imidazole ring, sulfhydryl, carboxamide, and carboxylate groups. Synthesized AaHNFs were characterized by their morphology and chemical point of view by using different techniques such as SEM, EDX, FTIR and XRD. Their peroxidase like activities were determined. Using the principle of Fenton's reaction, AaHNFs were found to be exhibitinga more effective peroxidase-like activity than free amino acids. We applied different analytical measurement methods such as hydrogen peroxide scavenging activity assay of AaHNFs and the assays of DPPH and ABTS radical scavenging activities to determine the anti-oxidant capacities of AaHNFs. AaHNFs can be evaluated as an effective anti-oxidant scavenger material due to their superior properties. This new type of HNFs can be exploited as a natural anti-oxidant in various potential applications related to fields such as biosensing, bioassay, biomedicine, pharmaceutics and biocatalysis.