MEDICINAL CHEMISTRY, vol.16, no.6, pp.735-749, 2020 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE, MEDLINE
EGFR/PI3K/AKT pathway, LNCaP, flurbiprofen, thioether, methionine aminopeptidase, prostate cancer, METHIONINE AMINOPEPTIDASE-2 INHIBITOR, ANTI-HCV, PROGRESSION, FUMAGILLIN, TNP-470
Kayseri University Affiliated:
Background: Prostate cancer is still one of the serious causes of mortality and morbidity in men. Despite recent advances in anticancer therapy, there is a still need of novel agents with more efficacy and specificity in the treatment of prostate cancer. Because of its function on angiogenesis and overexpression in the prostate cancer, methionine aminopeptidase-2 (MetAP-2) has been a potential target for novel drug design recently.