Atıf İçin Kopyala
Yilmaz O., Bayer B., Bekci H., Uba A., CUMAOĞLU A., Yelekci K., ...Daha Fazla
MEDICINAL CHEMISTRY, cilt.16, sa.6, ss.735-749, 2020 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
16
Sayı:
6
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Basım Tarihi:
2020
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Doi Numarası:
10.2174/1573406415666190613162322
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Dergi Adı:
MEDICINAL CHEMISTRY
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE, MEDLINE
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Sayfa Sayıları:
ss.735-749
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Anahtar Kelimeler:
EGFR/PI3K/AKT pathway, LNCaP, flurbiprofen, thioether, methionine aminopeptidase, prostate cancer, METHIONINE AMINOPEPTIDASE-2 INHIBITOR, ANTI-HCV, PROGRESSION, FUMAGILLIN, TNP-470
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Kayseri Üniversitesi Adresli:
Evet
Özet
Background: Prostate cancer is still one of the serious causes of mortality and morbidity in men. Despite recent advances in anticancer therapy, there is a still need of novel agents with more efficacy and specificity in the treatment of prostate cancer. Because of its function on angiogenesis and overexpression in the prostate cancer, methionine aminopeptidase-2 (MetAP-2) has been a potential target for novel drug design recently.