JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY, 2026 (SCI-Expanded, Scopus)
The increasing demand for eco-friendly and multifunctional nanomaterials has intensified interest in green synthesis strategies for biomedical and environmental applications. In this study, AgMgO nanocomposites (NCs) were successfully synthesized using Parmelia tiliaceae extract as a biological reducing and stabilizing agent. The synthesized NCs were comprehensively characterized by UV-Vis spectroscopy, SEM, STEM, DLS, FTIR, EDX, XRD, and TGA analyses, confirming their spherical morphology, homogeneous distribution, and particle size in the range of 20-80 nm. The biological and functional properties of the AgMgO NCs were systematically evaluated. The nanocomposites exhibited notable antibacterial activity, with a maximum inhibition zone of 17.3 +/- 0.5 mm against Escherichia coli O157:H7 ATCC 35150, and a strong antibiofilm effect, achieving up to 94% inhibition against Staphylococcus aureus ATCC 29213. In addition, effective antialgal activity was observed across all tested concentrations. The photocatalytic performance of the NCs demonstrated moderate efficiency, achieving 61.8% degradation of methylene blue (2 mg/L) within 180 min, indicating their potential as a proof-of-function system for environmental remediation. Furthermore, the synthesized NCs showed significant cytotoxic activity against A549 lung cancer cells. Overall, the results demonstrate that lichen-mediated AgMgO NCs are cost-effective, biocompatible, and multifunctional materials with promising applications in antimicrobial, environmental, and biomedical fields.