A reusable and sensitive electrochemical sensor for determination of Allura red in the presence of Tartrazine based on functionalized nanodiamond@SiO2@TiO2; an electrochemical and molecular docking investigation


Mehmandoust M., Pourhakkak P., Hasannia F., ÖZALP Ö., SOYLAK M., ERK N.

Food and Chemical Toxicology, vol.164, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 164
  • Publication Date: 2022
  • Doi Number: 10.1016/j.fct.2022.113080
  • Journal Name: Food and Chemical Toxicology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Chimica, EMBASE, Environment Index, Food Science & Technology Abstracts, MEDLINE, Pollution Abstracts, Veterinary Science Database
  • Keywords: Azo dye, Allura red, Voltammetry, F-nanodiamond, Silicon dioxide, Titanium dioxide, SOLID-PHASE EXTRACTION, DOUBLE-STRANDED DNA, VOLTAMMETRIC DETERMINATION, HIGH-PERFORMANCE, IONIC LIQUID, FOOD, NANOPARTICLES, NANOSENSOR, COLORANTS, CADMIUM
  • Kayseri University Affiliated: No

Abstract

© 2022 Elsevier LtdA sensitive and novel electrochemical sensor for the detection of Allura Red (AR) in the presence of tartrazine (TRZ) was fabricated using a screen-printed electrode modified by functionalized nanodiamond covered using silicon dioxide and titanium dioxide nanoparticles (F-nanodiamond@SiO2@TiO2/SPE). Scanning electron microscopy (SEM), brunauer–Emmett–teller (BET), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FT-IR) techniques were performed to characterize the as-synthesized Fnanodiamond@SiO2@TiO2 nanocomposite. The as-fabricated electrode demonstrated two wide dynamic ranges of 0.01–0.12 and 0.12–8.65 μM with a limit of detection (LOD) as low as 1.22 nM. Moreover, the modified electrode exhibits excellent repeatability, reproducibility, reusability, selectivity, and stability with high sensitivity of 44.3 μA μM−1 cm−1, offering good prospects in the simple, cost-effective, and rapid assessment of their total concentration. The successful detection of AR and TRZ, simultaneously and individually in food samples, revealed the applicability of the sensor in the determination of AR and TRZ with satisfactory recovery. Therefore, these advantages provide an excellent possibility for the smart monitoring of AR and TRZ in the future. In the final step, the preferential intercalative binding mode of Allura red with ds-DNA was approved for the first time by a molecular docking study. This study paves the way for engineering highly sensitive DNA biosensors to monitor azo dye compounds by combining the benefits of nanocomposites and valuable information of a molecular docking study.