Synthesis and Reactions of 4-Benzoyl-1,5-diaryl-1H-pyrazole-3-carbonyl Chlorides with Various Semi- and Thiosemicarbazides


Korkusuz E. , YILDIRIM İ.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.47, no.2, pp.472-476, 2010 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 2
  • Publication Date: 2010
  • Doi Number: 10.1002/jhet.306
  • Title of Journal : JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Page Numbers: pp.472-476

Abstract

The 1H-pyrazole-3-carboxylic acids 2 were converted via reactions of their acid chlorides 3 with some semi- and thiosemicarbazide derivatives into the corresponding new phenylsemi- and thiosemicarbazides 4a-e, 6, 5-(pyrazol-3-yl)-4H-1,2,4-triazol-3-thiones 5a,b, and 2-(pyrazol-3-yl)-1,3,4-thiadiazol 7 derivatives, in good yields (45-97%, respectively). The reactions of 4a,c,e with Lawesson reagent lead to the products 6 and 7 formation. The structures of these newly synthesized compounds were determined from the IR, H-1- and C-13-NMR spectroscopic data and elemental analyses.